|Biography:||I started my research experience in the field of ubiquitin proteasome system and proteomics in the Wellcome Trust Centre for Human Genetics, Oxford University, UK.|
I worked at Oxford University as a research assistant in mass spectrometry and protein biochemistry for over four years.
I completed my Ph.D. in Clinical Medicine at Oxford University , with my research interests being focused on protein deubiquitination, protein mass spectrometry and host-pathogen interactions.
I am now a research assistant professor at the Institute for Genomics, Biocomputing and Biotechnology (IGBB). My research relates to mass spectrometry-based proteomics and molecular aspects of the host-pathogen interactions during bacterial infection.
|Research Interest: ||- protein turnover and ubiquitin proteasome system|
- protein post-translational modifications (ubiquitination, phosphorylation, acetylation, methylation etc.) and their impact on protein function
- host-pathogen interactions (type three secretion bacteria: Salmonella, Shigella, Yersinia)
|Publications: ||Glinka, T., Alter, J., Braunstein, I., Tzach, L., Sheng, C. W., Geifman, S., Edelmann, M. J., Kessler, B., & Stanhill, A. (2013). Signal-peptide Mediated Translocation Is Regulated by a P97-AIRAPL Complex. Biochemical Journal. 1, 1-1. DOI:10.1042/BJ20130710. [Abstract] [Document Site]|
Hipp, M. M., Shepherd, D., Gileadi, U., Aichinger, M. C., Kessler, B. M., Edelmann, M. J., Essalmani, R., Seidah, N. G., Sousa, C. R., & Cerundolo, V. (2013). Processing of Human Toll-like Receptor 7 by Furin-like Proprotein Convertases Is Required for Its Accumulation and Activity in Endosomes. Immunity. Cell. 39(4), 711-721. [Document Site]
Edelmann, M. J., Kramer, H. B., & Kessler, B. M. (2010). Post-translational Modification of the Deubiquitinating Enzyme Otubain 1 Modulates Active RhoA Levels and Susceptibility to Yersinia Invasion. FEBS Journal. 277(11), 2515 – 2530. [Document Site]
Mortensen, M., Ferguson, D. J., Edelmann, M. J., Kessler, B., Morten, K. J., Komatsu, M., & Simon, A. K. (2010). Loss of Autophagy in Erythroid Cells Leads to Defective Removal of Mitochondria and Severe Anemia in Vivo. PNAS. 107(2), 832-7. [Document Site]
Edelmann, M. J., Iphöfer, A., Akutsu, M., Altun, M., DiGleria, K., Kramer, H. B., Fiebiger, E., Dhe-Paganon, S., & Kessler, B. M. (2009). Structural Basis and Specificity of Human Otubain 1-mediated Deubiquitination. Biochemistry Journal. 418(2), 379-90. [Document Site]
|Total Publications by this Author: 42|